ccx-354
Small moleculeexperimental
Clinical trial activity
2 trials · 1 clinical orgs · 0 marketing orgs
Phase 1
1
Phase 2
2
Phase 3
0
Phase 4
0
Earliest trial started Dec 1, 2009 (NCT01027728)
Timeline
Indications
Studied for
Mechanism of action
- C-C chemokine receptor type 1ANTAGONIST
CCR1 antagonist
Chemistry & pharmacology
Loading structure…
SMILES
COc1cc(N2CCN(C(=O)Cn3nc(-c4ncc[nH]4)c4cccnc43)CC2)ccc1Cl- Mol. weight
- 451.92 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL4444976 ↗
- ChEMBLCHEMBL3545404 ↗
Also known as
- ccx354
- ccx354
- ccx-354
- ccx-354
- ccx-354
- ccx-354-c
- ccx354-c
- ccx354-c
- ccx354-c
- gsk2941266
- gsk2941266
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01242917 | Phase 2 | Sep 1, 2010 | ChemoCentryx |
| NCT01027728 | Phase 1/Phase 2 (Phase 2) | Dec 1, 2009 | ChemoCentryx |
Showing 2 of 2 trials
Page 1 / 1
Organizations
Research & Development (1)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| ChemoCentryx | For profit | 2 | 2 | 1 | 2009 |
1 organizations
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