acetyl hexapeptide-8

Peptideexperimental

Acetyl hexapeptide-8, also known as acetyl hexapeptide-8 amide, is a synthetic hexapeptide used as a topical cosmetic ingredient that may improve the appearance of wrinkles. It is a small peptide fragment of SNAP25, a protein involved in neurotransmitter release and one of the targets of botulinum toxin type A, commonly known as Botox. — Wikipedia

Clinical trial activity

4 trials · 6 clinical orgs · 0 marketing orgs

Phase 1
1
Phase 2
3
Phase 3
1
Phase 4
0

Earliest trial started Mar 1, 2009 (NCT01381484)

Timeline

2000s

  1. Jan 1, 2009

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2009

    Earliest Phase 3 Sponsor(trial)

2010s

  1. Jan 1, 2012

    Earliest Phase 2 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • ac-eemqrr-nh2
  • acetyl-glutamyl-glutamyl-methionyl-glutaminyl-arginyl-argininamide
  • acetyl-hexapeptide
  • acetyl-hexapeptide
  • acetyl hexapeptide-3
  • acetyl hexapeptide-3
  • acetyl hexapeptide-8
  • acetyl hexapeptide-8
  • acetyl hexapeptide-8
  • acetyl hexapeptide-8
  • argireline
  • argireline
  • argireline
  • argireline

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT02597777N/AJan 31, 2016University of California, Berkeley, University of California, Davis
NCT01750346Phase 2Nov 1, 2012National Institute of Neurological Disorders and Stroke (NINDS)
NCT00942851Phase 1/Phase 2 (Phase 2)Jul 1, 2009BCN Peptides, National Institute of Neurological Disorders and Stroke (NINDS)
NCT01381484Phase 3Mar 1, 2009Mahidol University, Pacific Health Foundation
Showing 4 of 4 trials
Page 1 / 1

Organizations

Research & Development (6)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
National Institute of Neurological Disorders and Stroke (NINDS)Government2212009
BCN PeptidesFor profit1012009
Mahidol UniversityAcademic/Hospital1112009
Pacific Health FoundationAcademic/Hospital1012009
University of California, BerkeleyAcademic/Hospital1012016
University of California, DavisAcademic/Hospital1112016
6 organizations
Page 1 / 1