zamicastat

Small moleculeexperimental

Clinical trial activity

15 trials · 4 clinical orgs · 0 marketing orgs

Phase 1
13
Phase 2
2
Phase 3
0
Phase 4
0

Earliest trial started Mar 1, 2011 (NCT02151994)

Timeline

2010s

  1. Jan 1, 2011

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2019

    Earliest Phase 2 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

Fc1cc(F)c2c(c1)C[C@@H](n1c(CCNCc3ccccc3)c[nH]c1=S)CO2
Mol. weight
401.48 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • bia 5-1058
  • yh22189
  • zamicastat
  • zamicastat
  • zamicastat

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06009185Phase 2Jun 26, 2019Bial
NCT04316143Phase 2Jun 6, 2019Bial
NCT04069130Phase 1Apr 8, 2019Bial
NCT03708146Phase 1Jun 24, 2018Bial
NCT07173738Phase 1Jun 11, 2018Bial, Simbec-Orion
NCT03489005Phase 1Apr 30, 2018Bial, Covance
NCT04994860Phase 1Mar 22, 2018Bial
NCT04675944Phase 1Feb 28, 2018Bial
NCT04994119Phase 1Feb 23, 2018Bial
NCT04991207Phase 1Feb 6, 2018Bial
NCT04991181Phase 1Mar 31, 2017Bial
NCT02608242Phase 1Nov 1, 2015Yuhan Pharmaceutical Company
NCT04991194Phase 1Oct 12, 2015Bial
NCT04991155Phase 1Jul 20, 2015Bial
NCT02151994Phase 1Mar 1, 2011Bial
Showing 15 of 15 trials
Page 1 / 1

Organizations

Research & Development (4)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
BialFor profit141422011
CovanceFor profit1012018
Simbec-OrionFor profit1012018
Yuhan Pharmaceutical CompanyFor profit1112015
4 organizations
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