reldesemtiv
Small moleculeexperimental
Clinical trial activity
6 trials · 2 clinical orgs · 0 marketing orgs
Phase 1
1
Phase 2
5
Phase 3
2
Phase 4
0
Earliest trial started Dec 1, 2015 (NCT02644668)
Timeline
Indications
Mechanism of action
- Fast skeletal troponin complexACTIVATOR
Fast skeletal troponin complex activator
- CalciumOTHER
Calcium
Chemistry & pharmacology
Loading structure…
SMILES
NC(=O)c1ccn(-c2cnc(NC[C@]3(c4ncccc4F)C[C@H](F)C3)nc2)c1- Mol. weight
- 384.39 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL4297600 ↗
Also known as
- ck-2127107
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05442775 | Phase 3 | Jul 25, 2022 | Cytokinetics |
| NCT04944784 | Phase 3 | Aug 16, 2021 | Cytokinetics |
| NCT03160898 | Phase 2 | Jun 1, 2017 | Astellas, Cytokinetics |
| NCT03065959 | Phase 1 | May 19, 2017 | Astellas, Cytokinetics |
| NCT02662582 | Phase 2 | Jun 30, 2016 | Astellas, Cytokinetics |
| NCT02644668 | Phase 2 | Dec 1, 2015 | Astellas, Cytokinetics |
Showing 6 of 6 trials
Page 1 / 1
Organizations
Research & Development (2)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Cytokinetics | For profit | 6 | 4 | 3 | 2015 |
| Astellas | For profit | 4 | 2 | 2 | 2015 |
2 organizations
Page 1 / 1