casirivimab
mAbexperimentalCOVID-19
Clinical trial activity
13 trials · 14 clinical orgs · 0 marketing orgs
Phase 1
4
Phase 2
8
Phase 3
3
Phase 4
2
Earliest trial started Nov 20, 2020 (NCT04840459)
Timeline
Indications
Approved for
Mechanism of action
- Spike glycoproteinANTAGONIST
Spike glycoprotein antagonist
- Spike glycoproteinINHIBITOR
Spike glycoprotein inhibitor
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL4650248 ↗
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05157997 | Phase 1 | Jan 31, 2022 | Northwell Health, Regeneron |
| NCT05181683 | Phase 1 | Jan 7, 2022 | Regeneron |
| NCT05092581 | Phase 1 | Dec 20, 2021 | Regeneron |
| NCT05205759 | Phase 3 | Dec 9, 2021 | Agenzia Italiana del Farmaco, University of Udine, University of Verona |
| NCT05081388 | Phase 1/Phase 2 (Phase 2) | Nov 8, 2021 | Regeneron |
| NCT05502081 | Phase 4 | Nov 1, 2021 | Tanta University |
| NCT05074433 | Phase 3 | Oct 25, 2021 | Regeneron |
| NCT05041907 | Phase 2 | Sep 30, 2021 | University of Oxford |
| NCT04992273 | Phase 2 | Sep 13, 2021 | Regeneron |
| NCT04852978 | Phase 2 | Apr 29, 2021 | Regeneron |
| NCT04790786 | Phase 3 | Mar 10, 2021 | Berry Consultants, University of Pittsburgh |
| NCT04748588 | Phase 4 | Feb 12, 2021 | University of British Columbia, University of Calgary, University of Toronto |
| NCT04840459 | Phase 2 | Nov 20, 2020 | DHR Health Institute for Research and Development, DHR Heath Institute for Research and Development |
Showing 13 of 13 trials
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Organizations
Research & Development (14)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Regeneron | For profit | 7 | 6 | 3 | 2021 |
| Agenzia Italiana del Farmaco | Government | 1 | 0 | 1 | 2021 |
| Berry Consultants | For profit | 1 | 0 | 1 | 2021 |
| DHR Health Institute for Research and Development | Academic/Hospital | 1 | 1 | 1 | 2020 |
| DHR Heath Institute for Research and Development | Academic/Hospital | 1 | 0 | 1 | 2020 |
| Northwell Health | Academic/Hospital | 1 | 1 | 1 | 2022 |
| Tanta University | Academic/Hospital | 1 | 0 | 1 | 2021 |
| University of British Columbia | Academic/Hospital | 1 | 0 | 1 | 2021 |
| University of Calgary | Academic/Hospital | 1 | 1 | 1 | 2021 |
| University of Oxford | Academic/Hospital | 1 | 1 | 1 | 2021 |
| University of Pittsburgh | Academic/Hospital | 1 | 1 | 1 | 2021 |
| University of Toronto | Academic/Hospital | 1 | 0 | 1 | 2021 |
| University of Udine | Academic/Hospital | 1 | 0 | 1 | 2021 |
| University of Verona | Academic/Hospital | 1 | 1 | 1 | 2021 |
14 organizations
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