novel oral polio vaccine type 1 (nopv1)
Vaccineexperimental
Clinical trial activity
6 trials · 17 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
4
Phase 3
1
Phase 4
1
Earliest trial started May 1, 2013 (NCT02093273)
Timeline
Indications
Approved for
Mechanism of action
- PoliovirusImmunity, active
Poliovirus immunity, active
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- topv
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06895486 | Phase 2 | Sep 29, 2025 | Bill and Melinda Gates Foundation, Centers for Disease Control and Prevention (CDC), Cevaxin, PATH, PT Bio Farma, Technical Resources International, Inc. (TRI) |
| NCT06137664 | Phase 1/Phase 2 (Phase 2) | Dec 29, 2023 | PATH |
| NCT04529538 | Phase 1 | Jan 31, 2021 | Bill and Melinda Gates Foundation, Centers for Disease Control and Prevention (CDC), Dartmouth University, PATH, The EMMES Corporation, University of North Carolina at Chapel Hill, University of Vermont, Viroclinics Biosciences B.V. |
| NCT02477046 | Phase 3 | Apr 1, 2015 | Bill and Melinda Gates Foundation, International Center for Diarrheal Disease Research, University of Virginia |
| NCT02189811 | Phase 4 | Sep 1, 2014 | Aga Khan University, Centers for Disease Control and Prevention (CDC), National Institutes of Health (NIH), World Health Organization |
| NCT02093273 | Phase 2 | May 1, 2013 | Padjadjaran University, PT Bio Farma |
Showing 6 of 6 trials
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Organizations
Research & Development (17)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Bill and Melinda Gates Foundation | Academic/Hospital | 3 | 0 | 3 | 2015 |
| Centers for Disease Control and Prevention (CDC) | Government | 3 | 0 | 3 | 2014 |
| PATH | Academic/Hospital | 3 | 3 | 2 | 2021 |
| PT Bio Farma | For profit | 2 | 1 | 1 | 2013 |
| Aga Khan University | Academic/Hospital | 1 | 1 | 1 | 2014 |
| Cevaxin | Academic/Hospital | 1 | 0 | 1 | 2025 |
| Dartmouth University | Academic/Hospital | 1 | 0 | 1 | 2021 |
| International Center for Diarrheal Disease Research | Academic/Hospital | 1 | 0 | 1 | 2015 |
| National Institutes of Health (NIH) | Government | 1 | 0 | 1 | 2014 |
| Padjadjaran University | Academic/Hospital | 1 | 0 | 1 | 2013 |
| Technical Resources International, Inc. (TRI) | For profit | 1 | 0 | 1 | 2025 |
| The EMMES Corporation | For profit | 1 | 0 | 1 | 2021 |
| University of North Carolina at Chapel Hill | Academic/Hospital | 1 | 0 | 1 | 2021 |
| University of Vermont | Academic/Hospital | 1 | 0 | 1 | 2021 |
| University of Virginia | Academic/Hospital | 1 | 1 | 1 | 2015 |
| Viroclinics Biosciences B.V. | For profit | 1 | 0 | 1 | 2021 |
| World Health Organization | Government | 1 | 0 | 1 | 2014 |
17 organizations
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