avicin d

Small moleculeexperimental

Avicin D, a natural triterpenoid saponin, is a selective glucocorticoid receptor (GR) modulator. It has been approved by the United States Food and Drug Administration for phase I studies in human cancer patients. In addition, avicin D has the therapeutic potential for patients with Sézary syndrome. — NCATS

Clinical trial activity

0 trials · 0 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0

Chemistry & pharmacology

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SMILES

C[C@H]1O[C@@H](OC[C@H]2O[C@@H](O[C@H]3CC[C@@]4(C)[C@@H](CC[C@]5(C)[C@@H]4CC=C6[C@@H]7CC(C)(C)[C@H](C[C@@]7([C@H](O)C[C@@]56C)C(=O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O[C@@H]9O[C@@H](C)[C@H](O[C@@H]%10O[C@@H](CO)[C@H](O)[C@H]%10O)[C@@H](O[C@@H]%11O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%11O)[C@H]9O)OC(=O)C(\CO)=C\CC[C@@](C)(O[C@@H]%12O[C@H](C)[C@@H](OC(=O)C(\CO)=C\CC[C@@](C)(O)C=C)[C@H](O)[C@H]%12O)C=C)C3(C)C)[C@H](NC(C)=O)[C@@H](O)[C@@H]2O)[C@H](O[C@@H]%13OC[C@@H](O)[C@H](O)[C@H]%13O)[C@@H](O)[C@H]1O
Mol. weight
2083.2584 g/mol

Oral

No

Parenteral

No

Topical

No

Sources