at-1501
mAbexperimental
Clinical trial activity
9 trials · 6 clinical orgs · 0 marketing orgs
Phase 1
4
Phase 2
8
Phase 3
0
Phase 4
0
Earliest trial started Mar 31, 2020 (NCT04322149)
Timeline
Indications
Studied for
- Amyotrophic Lateral Sclerosis · Phase 2
- Diabetes Mellitus · Phase 1/Phase 2
- Diabetes Mellitus, Type 1 · Phase 2
- Diabetic Nephropathies · Phase 2
- Glomerulonephritis, IGA · Phase 2
- Graft Rejection · Phase 1/Phase 2
- Immunosuppression Therapy · Early Phase 1
- Kidney Transplantation · Phase 2
- Renal Insufficiency · Early Phase 1
Mechanism of action
- CD40 ligandINHIBITOR
CD40LG inhibitor
Chemistry & pharmacology
- Inorganic
- No
- Polymer
- No
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Sources
- NCATSEK87C62XNH ↗
- ChEMBLCHEMBL4594460 ↗
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06972069 | Early Phase 1 (Phase 1) | May 31, 2025 | Eledon Pharmaceuticals, Harvard University, ITB-Med LLC |
| NCT06305286 | Phase 1/Phase 2 (Phase 2) | Mar 4, 2024 | Juvenile Diabetes Research Foundation, University of Chicago |
| NCT06126380 | Phase 2 | Oct 25, 2023 | Eledon Pharmaceuticals |
| NCT05983770 | Phase 2 | Aug 30, 2023 | Eledon Pharmaceuticals |
| NCT05480657 | Phase 1/Phase 2 (Phase 2) | Sep 30, 2022 | Eledon Pharmaceuticals |
| NCT05125068 | Phase 2 | Jan 31, 2022 | Eledon Pharmaceuticals |
| NCT05027906 | Phase 1/Phase 2 (Phase 2) | Nov 30, 2021 | Eledon Pharmaceuticals |
| NCT04711226 | Phase 2 | Feb 19, 2021 | Eledon Pharmaceuticals, Novus Pharma |
| NCT04322149 | Phase 2 | Mar 31, 2020 | Novus Pharma |
Showing 9 of 9 trials
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Organizations
Research & Development (6)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Eledon Pharmaceuticals | For profit | 7 | 5 | 2 | 2021 |
| Novus Pharma | For profit | 2 | 2 | 1 | 2020 |
| Harvard University | Academic/Hospital | 1 | 1 | 1 | 2025 |
| ITB-Med LLC | For profit | 1 | 0 | 1 | 2025 |
| Juvenile Diabetes Research Foundation | Academic/Hospital | 1 | 0 | 1 | 2024 |
| University of Chicago | Academic/Hospital | 1 | 1 | 1 | 2024 |
6 organizations
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