ethyl nitrate
Small moleculeexperimental
Ethyl nitrate is an inhaled organic nitrate that affects pulmonary vascular tone and may be used as a possible treatment for persistent pulmonary hypertension of the newborn. Ethyl nitrate acts by generating NO, which activates soluble guanylate cyclase to increase intracellular cyclic GMP. This, in turn, leads to a decrease in intracellular calcium and relaxation of the vascular smooth muscle. — NCATS
Clinical trial activity
0 trials · 0 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Chemistry & pharmacology
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SMILES
CCO[N+]([O-])=O- Mol. weight
- 91.066 g/mol
Oral
No
Parenteral
No
Topical
No
Sources
- NCATSE1ZT886LR5 ↗