4-hydroxyifosfamide

Small moleculeexperimental

Ifosfamide (IF) is a widely used antitumor prodrug. It is in the oxazaphosphorine class of alkylating agents, and it is effective against solid tumors. Ifosfamide mechanism of crosslinking DNA plays a major role in preventing cancer cells from proliferating. Ifosfamide is approved by FDA for the treatment of germ cell testicular cancer. — NCATS

Clinical trial activity

0 trials · 0 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0

Indications

Chemistry & pharmacology

Loading structure…

SMILES

OC1CCOP(=O)(NCCCl)N1CCCl
Mol. weight
277.085 g/mol

Oral

No

Parenteral

No

Topical

No

Sources