skb264
mAbexperimentalImaging agent
Clinical trial activity
58 trials · 21 clinical orgs · 0 marketing orgs
Phase 1
10
Phase 2
56
Phase 3
23
Phase 4
0
Earliest trial started Dec 31, 2019 (NCT04152499)
Timeline
Indications
Studied for
- B7-H1 Antigen · Phase 1
- Biliary Tract Neoplasms · Phase 1/Phase 2
- Bone Marrow Diseases · Phase 2
- Breast Neoplasms · Phase 3
- Carcinoma, Non-Small-Cell Lung · Phase 3
- Carcinoma, Ovarian Epithelial · Phase 1/Phase 2
- Carcinoma, Transitional Cell · Phase 1/Phase 2
- Cholangiocarcinoma · Phase 2
- Colorectal Neoplasms · Phase 1/Phase 2
- Drugs, Investigational · Phase 2
- Endometrial Neoplasms · Phase 3
- Epidermal Growth Factor · Phase 2
- Esophageal Neoplasms · Phase 3
- Esophageal Squamous Cell Carcinoma · Phase 2
- Esophagogastric Junction · Phase 1/Phase 2
- Fallopian Tube Neoplasms · Phase 3
- Hamartoma · Phase 3
- Lung Neoplasms · Phase 2
- Neoadjuvant Therapy · Phase 2
- Neoplasms · Phase 2
- Ovarian Neoplasms · Phase 3
- Pancreatic Neoplasms · Phase 1/Phase 2
- Programmed Cell Death 1 Ligand 2 Protein · Phase 1
- Programmed Cell Death 1 Receptor · Phase 1
- Prostatic Neoplasms · Phase 2
- Prostatic Neoplasms, Castration-Resistant · Phase 2
- Small Cell Lung Carcinoma · Phase 1/Phase 2
- Squamous Cell Carcinoma of Head and Neck · Phase 2
- Stomach Neoplasms · Phase 1/Phase 2
- Triple Negative Breast Neoplasms · Phase 3
- Urinary Bladder Neoplasms · Phase 1/Phase 2
- Uterine Cervical Neoplasms · Phase 3
Mechanism of action
TACSTD2 inhibitor
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Multi-specific
- No
- Imaging
- belotecan
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL5314875 ↗
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07286149 | Phase 1/Phase 2 (Phase 2) | Feb 9, 2026 | Daiichi Sankyo, Merck |
| NCT07244926 | Phase 2 | Dec 31, 2025 | Tianjin Medical University |
| NCT07256236 | Phase 2 | Dec 15, 2025 | Fujian Medical University |
| NCT07244874 | Phase 2 | Dec 1, 2025 | People's Liberation Army of China, Tianjin Medical University |
| NCT07216703 | Phase 3 | Nov 18, 2025 | Merck |
| NCT07193160 | Phase 2 | Nov 1, 2025 | Fudan University |
| NCT07054242 | Phase 2 | Oct 30, 2025 | Qingdao University, Sichuan Kelun Pharmaceutical Research Institute Co., Ltd. |
| NCT07197008 | Phase 2 | Oct 1, 2025 | Sun Yat-Sen University |
| NCT07109284 | Phase 2 | Sep 30, 2025 | Sichuan University |
| NCT07182721 | Phase 2 | Sep 30, 2025 | Fudan University |
| NCT07128693 | Phase 2 | Sep 30, 2025 | Zhengzhou University |
| NCT07179783 | Phase 2 | Sep 22, 2025 | Sichuan Kelun Pharmaceutical Research Institute Co., Ltd., Tianjin Medical University |
| NCT07157956 | Phase 1/Phase 2 (Phase 2) | Sep 10, 2025 | Convalife, Sun Yat-Sen University |
| NCT07153965 | Phase 2 | Sep 1, 2025 | Tianjin Medical University |
| NCT07007780 | Phase 2 | Aug 20, 2025 | Xijing Hospital |
| NCT07139470 | Phase 1/Phase 2 (Phase 2) | Aug 15, 2025 | Tianjin Medical University |
| NCT07108816 | Phase 2 | Aug 15, 2025 | Henan Medical University |
| NCT07068542 | N/A | Aug 1, 2025 | Zhejiang University |
| NCT07088211 | Phase 2 | Jul 31, 2025 | Jiao Tong University |
| NCT07077564 | Phase 2 | Jul 20, 2025 | Zhejiang University |
Showing 20 of 58 trials
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Organizations
Research & Development (21)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Merck | For profit | 23 | 23 | 3 | 2023 |
| Sichuan Kelun Pharmaceutical Research Institute Co., Ltd. | For profit | 14 | 11 | 2 | 2022 |
| Tianjin Medical University | Academic/Hospital | 5 | 5 | 1 | 2025 |
| European Network for Gynaecological Oncological Trial | Academic/Hospital | 3 | 0 | 1 | 2023 |
| Fudan University | Academic/Hospital | 3 | 3 | 1 | 2025 |
| GOG Foundation, Inc. | Academic/Hospital | 3 | 0 | 1 | 2023 |
| Klus Pharma Inc. | For profit | 3 | 3 | 1 | 2019 |
| Zhejiang University | Academic/Hospital | 3 | 3 | 2 | 2025 |
| Sun Yat-Sen University | Academic/Hospital | 2 | 1 | 1 | 2025 |
| Convalife | For profit | 1 | 1 | 1 | 2025 |
| Daiichi Sankyo | For profit | 1 | 0 | 1 | 2026 |
| Fujian Medical University | Academic/Hospital | 1 | 1 | 1 | 2025 |
| Henan Medical University | Academic/Hospital | 1 | 1 | 1 | 2025 |
| Jiao Tong University | Academic/Hospital | 1 | 1 | 1 | 2025 |
| People's Liberation Army of China | Government | 1 | 0 | 1 | 2025 |
| Qingdao University | Academic/Hospital | 1 | 1 | 1 | 2025 |
| Sichuan University | Academic/Hospital | 1 | 1 | 1 | 2025 |
| University of Texas at Houston | Academic/Hospital | 1 | 0 | 1 | 2019 |
| Xiamen University | Academic/Hospital | 1 | 1 | 1 | 2025 |
| Xijing Hospital | Academic/Hospital | 1 | 1 | 1 | 2025 |
21 organizations
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