car-cldn18.2 t-cells
Cell therapyexperimental
Clinical trial activity
8 trials · 11 clinical orgs · 0 marketing orgs
Phase 1
6
Phase 2
1
Phase 3
0
Phase 4
0
Earliest trial started Mar 26, 2019 (NCT03874897)
Timeline
2010s
- Jan 1, 2019
Earliest Phase 1 Sponsor(trial)
Indications
Mechanism of action
- Claudin-18Immunity, passive
CLDN18 immunity, passive
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07266311 | Early Phase 1 (Phase 1) | Dec 15, 2025 | Government of China, People's Liberation Army of China |
| NCT07066995 | Phase 1/Phase 2 (Phase 2) | Apr 29, 2025 | Essen Biotech |
| NCT06946615 | Phase 1 | Apr 8, 2025 | Zhejiang University |
| NCT06353152 | Phase 1 | Nov 17, 2023 | Gracell Biotechnology Ltd., Peking University |
| NCT05952375 | N/A | Mar 1, 2023 | Qingdao University |
| NCT05620732 | N/A | Oct 1, 2022 | Shenzhen University |
| NCT05472857 | Phase 1 | Aug 8, 2022 | Changhai Hospital, Government of China |
| NCT03874897 | Phase 1 | Mar 26, 2019 | CARsgen Therapeutics, Ltd., Chinese Academy of Medical Sciences, Peking University |
Showing 8 of 8 trials
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Organizations
Research & Development (11)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Government of China | Government | 2 | 2 | 1 | 2022 |
| Peking University | Academic/Hospital | 2 | 2 | 1 | 2019 |
| CARsgen Therapeutics, Ltd. | For profit | 1 | 0 | 1 | 2019 |
| Changhai Hospital | Academic/Hospital | 1 | 0 | 1 | 2022 |
| Chinese Academy of Medical Sciences | Academic/Hospital | 1 | 0 | 1 | 2019 |
| Essen Biotech | For profit | 1 | 1 | 1 | 2025 |
| Gracell Biotechnology Ltd. | For profit | 1 | 0 | 1 | 2023 |
| People's Liberation Army of China | Government | 1 | 0 | 1 | 2025 |
| Qingdao University | Academic/Hospital | 1 | 1 | 1 | 2023 |
| Shenzhen University | Academic/Hospital | 1 | 1 | 1 | 2022 |
| Zhejiang University | Academic/Hospital | 1 | 1 | 1 | 2025 |
11 organizations
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