alpha-pinene
α-Pinene is an organic compound of the terpene class. It is one of the two isomers of pinene, the other being β-pinene. An alkene, it contains a strained four-membered ring. It is found in the oils of many species of coniferous trees, notably Pinus and Picea species. It is also found in the essential oil of rosemary and Satureja myrtifolia. Both enantiomers are known in nature; (1S,5S)- or (−)-α-pinene is more common in European pines, whereas the (1R,5R)- or (+)-α-isomer is more common in North America. The enantiomers' racemic mixture is present in some oils such as eucalyptus oil and orange peel oil. — Wikipedia
Clinical trial activity
1 trials · 2 clinical orgs · 0 marketing orgs
Earliest trial started Feb 29, 2020 (NCT04130633)
Timeline
2020s
- Jan 1, 2020
Earliest Phase 1 Sponsor(trial)
Indications
Mechanism of action
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
SMILES
CC1=CCC2CC1C2(C)C- Mol. weight
- 136.24 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- Yes
- Chirality
- Racemic Mixture
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaΑ-Pinene ↗
- ChEMBLCHEMBL442565 ↗
- WikipediaAlpha-Pinene ↗
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04130633 | Phase 1 | Feb 29, 2020 | Johns Hopkins University, National Institute on Drug Abuse (NIDA) |
Organizations
Research & Development (2)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Johns Hopkins University | Academic/Hospital | 1 | 1 | 1 | 2020 |
| National Institute on Drug Abuse (NIDA) | Government | 1 | 0 | 1 | 2020 |