asp5354

Small moleculeexperimentalImaging agent

Clinical trial activity

7 trials · 1 clinical orgs · 0 marketing orgs

Phase 1

Phase 2

Phase 3

Phase 4

Earliest trial started Oct 25, 2018 (NCT03698305)

Timeline

2010s

Jan 1, 2018
Earliest Phase 1 Sponsor(trial)

2020s

Jan 1, 2020
Earliest Phase 2 Sponsor(trial)
Jan 1, 2023
Earliest Phase 3 Sponsor(trial)

Indications

Studied for

Mechanism of action

UnclearUnclear
Unclear unclear

Chemistry & pharmacology

Loading structure…

SMILES

COC1=C(/C=C/C2=[N+](CCC(=O)NCCCO[C@H]3[C@H]4O[C@H]5[C@H](O)[C@@H](O)[C@@H](O[C@H]6[C@H](O)[C@@H](O)[C@@H](O[C@H]7[C@H](O)[C@@H](O)[C@@H](O[C@H]8[C@H](O)[C@@H](O)[C@@H](O[C@H]9[C@H](O)[C@@H](O)[C@@H](O[C@H]%10[C@H](O)[C@@H](O)[C@@H](O[C@@H]([C@@H]3O)[C@@H](CO)O4)O[C@@H]%10CO)O[C@@H]9CO)O[C@@H]8CO)O[C@@H]7CO)O[C@@H]6CO)O[C@@H]5CO)c3ccc4ccccc4c3C2(C)C)CCC/C1=C\C=C1\N(CCC(=O)NCCCO[C@H]2[C@H]3O[C@H]4[C@H](O)[C@@H](O)[C@@H](O[C@H]5[C@H](O)[C@@H](O)[C@@H](O[C@H]6[C@H](O)[C@@H](O)[C@@H](O[C@H]7[C@H](O)[C@@H](O)[C@@H](O[C@H]8[C@H](O)[C@@H](O)[C@@H](O[C@H]9[C@H](O)[C@@H](O)[C@@H](O[C@@H]([C@@H]2O)[C@@H](CO)O3)O[C@@H]9CO)O[C@@H]8CO)O[C@@H]7CO)O[C@@H]6CO)O[C@@H]5CO)O[C@@H]4CO)c2ccc3ccccc3c2C1(C)C.[Cl-]

Mol. weight: 3079.47 g/mol
Chirality: Single Stereoisomer
Inorganic: No
Polymer: No

Oral

Parenteral

Topical

Sources

ChEMBLCHEMBL4802245 ↗

Clinical trials

NCT ID	Phase	Start date	Sponsor(s)
NCT05999747	Phase 3	Dec 31, 2023	Astellas
NCT05754333	Phase 3	Jun 30, 2023	Astellas
NCT05495581	Phase 1	Aug 25, 2022	Astellas
NCT05457842	Phase 2	Aug 10, 2022	Astellas
NCT04878471	Phase 1	Jun 2, 2021	Astellas
NCT04238481	Phase 2	Feb 29, 2020	Astellas
NCT03698305	Phase 1	Oct 25, 2018	Astellas

Showing 7 of 7 trials

Page 1 / 1

Organizations

Research & Development (1)

Organization	Org type	Trials	As lead sponsor	Phases	Earliest year
Astellas	For profit	7	7	3	2018

1 organizations

Page 1 / 1