pancreatin
Pancreatic enzymes, also known as pancreases, pancrelipases or pancreatins are commercial mixtures of amylase, lipase, protease and lactase obtained from pigs. The components are digestive enzymes similar to those normally produced by the human pancreas. They help in the digestion of fats, starches, and proteins. They are used to treat malabsorption syndrome due to certain pancreatic insufficiencies. These pancreatic problems may be due to cystic fibrosis, surgical removal of the pancreas, long-term pancreatitis, pancreatic cancer, or MODY 5, among others. The preparation is taken by mouth. The treatment is also known as pancreatic enzyme replacement therapy or PERT. — Wikipedia
Clinical trial activity
11 trials · 11 clinical orgs · 0 marketing orgs
Earliest trial started Oct 1, 2011 (NCT01587534)
Timeline
Indications
Approved for
Mechanism of action
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaPancreatic enzymes (medication) ↗
Also known as
- norzyme
- porcine pert
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05989958 | Phase 1 | Sep 22, 2023 | Capital Medical University, Hexaell Biotech Co., Ltd |
| NCT05261997 | N/A | Mar 31, 2022 | Changhai Hospital |
| NCT05112328 | N/A | Jul 7, 2021 | Seoul National University |
| NCT04786795 | Phase 4 | Mar 1, 2021 | Jiao Tong University |
| NCT04375878 | Phase 2 | Jul 1, 2020 | AzurRx |
| NCT04057326 | N/A | Aug 30, 2019 | Shenzhen Kangzhe Pharmaceutical Co., Ltd. |
| NCT03746483 | Phase 2 | Jan 10, 2019 | AzurRx |
| NCT03051490 | Phase 3 | Apr 28, 2017 | Anthera Pharmaceuticals |
| NCT02279498 | Phase 3 | Jun 1, 2015 | Anthera Pharmaceuticals |
| NCT02127021 | Phase 4 | Apr 1, 2014 | Pharmbio Korea, Seoul National University |
| NCT01587534 | Phase 2 | Oct 1, 2011 | National Cancer Center, Korea, Pharmbio Korea, The National Cancer Center |
Organizations
Research & Development (11)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Anthera Pharmaceuticals | For profit | 2 | 2 | 1 | 2015 |
| AzurRx | For profit | 2 | 2 | 1 | 2019 |
| Pharmbio Korea | For profit | 2 | 0 | 2 | 2011 |
| Seoul National University | Academic/Hospital | 2 | 2 | 2 | 2014 |
| Capital Medical University | Academic/Hospital | 1 | 0 | 1 | 2023 |
| Changhai Hospital | Academic/Hospital | 1 | 1 | 1 | 2022 |
| Hexaell Biotech Co., Ltd | For profit | 1 | 1 | 1 | 2023 |
| Jiao Tong University | Academic/Hospital | 1 | 1 | 1 | 2021 |
| National Cancer Center, Korea | Government | 1 | 1 | 1 | 2011 |
| Shenzhen Kangzhe Pharmaceutical Co., Ltd. | For profit | 1 | 1 | 1 | 2019 |
| The National Cancer Center | Academic/Hospital | 1 | 0 | 1 | 2011 |