j147
Small moleculeexperimental
J147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. — Wikipedia
Clinical trial activity
1 trials · 3 clinical orgs · 0 marketing orgs
Phase 1
1
Phase 2
0
Phase 3
0
Phase 4
0
Earliest trial started Jan 22, 2019 (NCT03838185)
Timeline
2010s
- Jan 1, 2019
Earliest Phase 1 Sponsor(trial)
Indications
Studied for
Mechanism of action
PRKAB1 inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
COc1cccc(/C=N/N(C(=O)C(F)(F)F)c2ccc(C)cc2C)c1- Mol. weight
- 350.34 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaJ147 ↗
- ChEMBLCHEMBL2387144 ↗
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03838185 | Phase 1 | Jan 22, 2019 | Abrexa Pharmaceuticals, Inc., IQVIA, Vince & Associates |
Showing 1 of 1 trials
Page 1 / 1
Organizations
Research & Development (3)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Abrexa Pharmaceuticals, Inc. | For profit | 1 | 1 | 1 | 2019 |
| IQVIA | For profit | 1 | 0 | 1 | 2019 |
| Vince & Associates | For profit | 1 | 0 | 1 | 2019 |
3 organizations
Page 1 / 1