fucose
Small moleculeexperimental
Fucose is a hexose deoxy sugar with the chemical formula C6H12O5. It is found on N-linked glycans on the mammalian, insect and plant cell surface. Fucose is the fundamental sub-unit of the seaweed polysaccharide fucoidan. The α(1→3) linked core of fucoidan is a suspected carbohydrate antigen for IgE-mediated allergy. — Wikipedia
Clinical trial activity
3 trials · 2 clinical orgs · 0 marketing orgs
Phase 1
1
Phase 2
3
Phase 3
2
Phase 4
0
Earliest trial started Jan 1, 2012 (NCT03354533)
Timeline
Indications
Studied for
Mechanism of action
- L-fucose kinaseSUBSTRATE
FCSK substrate
Chemistry & pharmacology
Loading structure…
SMILES
C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C=O- Mol. weight
- 164.1565 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaFucose ↗
- NCATS28RYY2IV3F ↗
- ChEMBLCHEMBL6067643 ↗
- ChEMBLCHEMBL469449 ↗
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05754450 | Phase 3 | Apr 10, 2023 | Avalo Therapeutics, Inc. |
| NCT05462587 | Phase 3 | Jul 28, 2022 | Avalo Therapeutics, Inc. |
| NCT03354533 | Phase 1/Phase 2 (Phase 2) | Jan 1, 2012 | Orpha Labs |
Showing 3 of 3 trials
Page 1 / 1
Organizations
Research & Development (2)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Avalo Therapeutics, Inc. | For profit | 2 | 2 | 1 | 2022 |
| Orpha Labs | For profit | 1 | 1 | 1 | 2012 |
2 organizations
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