Polyhexanide
Small moleculeexperimental
Polyhexanide is a polymer used as a disinfectant and antiseptic. In dermatological use, it is spelled polihexanide (INN) and sold under various brand names. PHMB has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Candida albicans, Aspergillus brasiliensis, enterococci, and Klebsiella pneumoniae. Polihexanide, sold under the brand name Akantior is a medication used for the treatment of Acanthamoeba keratitis. — Wikipedia
Clinical trial activity
6 trials · 21 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
3
Phase 3
2
Phase 4
2
Earliest trial started Aug 13, 2017 (NCT03274895)
Timeline
Indications
Mechanism of action
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaPolyhexanide ↗
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06633588 | Phase 4 | Nov 18, 2024 | Swiss Paraplegic Centre Nottwil |
| NCT06213649 | Phase 3 | Jul 1, 2024 | Aravind Eye Hospital, Columbia University, Federal University of Sao Paulo, Johns Hopkins University, National Eye Institute (NEI), Oregon Health and Science University, University of California, Los Angeles, University of California, San Francisco, University of Florida, University of Illinois at Chicago, University of Iowa, University of London, University of Miami, University of Michigan, University of Pennsylvania |
| NCT06309368 | Phase 4 | Mar 14, 2024 | University of Nevada, Las Vegas |
| NCT06718777 | N/A | Aug 1, 2023 | Şırnak Üniversitesi |
| NCT05306431 | Phase 2 | Aug 1, 2022 | Altamash Institute of Dental Medicine |
| NCT03274895 | Phase 3 | Aug 13, 2017 | Moorfield's Hospital London, SIFI SpA |
Showing 6 of 6 trials
Page 1 / 1
Organizations
Research & Development (21)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Altamash Institute of Dental Medicine | Academic/Hospital | 1 | 1 | 1 | 2022 |
| Aravind Eye Hospital | Academic/Hospital | 1 | 0 | 1 | 2024 |
| Columbia University | Academic/Hospital | 1 | 0 | 1 | 2024 |
| Federal University of Sao Paulo | Academic/Hospital | 1 | 0 | 1 | 2024 |
| Johns Hopkins University | Academic/Hospital | 1 | 0 | 1 | 2024 |
| Moorfield's Hospital London | Academic/Hospital | 1 | 0 | 1 | 2017 |
| National Eye Institute (NEI) | Government | 1 | 0 | 1 | 2024 |
| Oregon Health and Science University | Academic/Hospital | 1 | 0 | 1 | 2024 |
| SIFI SpA | For profit | 1 | 1 | 1 | 2017 |
| Şırnak Üniversitesi | Academic/Hospital | 1 | 1 | 1 | 2023 |
| Swiss Paraplegic Centre Nottwil | Academic/Hospital | 1 | 1 | 1 | 2024 |
| University of California, Los Angeles | Academic/Hospital | 1 | 0 | 1 | 2024 |
| University of California, San Francisco | Academic/Hospital | 1 | 1 | 1 | 2024 |
| University of Florida | Academic/Hospital | 1 | 0 | 1 | 2024 |
| University of Illinois at Chicago | Academic/Hospital | 1 | 0 | 1 | 2024 |
| University of Iowa | Academic/Hospital | 1 | 0 | 1 | 2024 |
| University of London | Academic/Hospital | 1 | 0 | 1 | 2024 |
| University of Miami | Academic/Hospital | 1 | 0 | 1 | 2024 |
| University of Michigan | Academic/Hospital | 1 | 0 | 1 | 2024 |
| University of Nevada, Las Vegas | Academic/Hospital | 1 | 1 | 1 | 2024 |
21 organizations
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