benapenem
Small moleculeexperimental
Clinical trial activity
3 trials · 2 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
0
Phase 3
1
Phase 4
0
Earliest trial started Mar 11, 2015 (NCT03588156)
Timeline
Indications
Mechanism of action
- Beta LactamaseINHIBITOR
bla(tem-2) inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
C[C@@H](O)[C@H]1C(=O)N2C(C(=O)O)=C(S[C@@H]3CN[C@H](C(=O)NCc4ccc(S(N)(=O)=O)cc4)C3)[C@H](C)[C@H]12- Mol. weight
- 524.62 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL5095168 ↗
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04476407 | Phase 1 | Jun 15, 2019 | Sihuan Pharmaceutical Holdings Group Ltd. |
| NCT04505683 | Phase 2/Phase 3 (Phase 3) | Dec 13, 2018 | Sihuan Pharmaceutical Holdings Group Ltd. |
| NCT03588156 | Phase 1 | Mar 11, 2015 | Peking University, Sihuan Pharmaceutical Holdings Group Ltd. |
Showing 3 of 3 trials
Page 1 / 1
Organizations
Research & Development (2)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Sihuan Pharmaceutical Holdings Group Ltd. | For profit | 3 | 3 | 2 | 2015 |
| Peking University | Academic/Hospital | 1 | 0 | 1 | 2015 |
2 organizations
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