tcr-t cells
Cell therapyexperimental
Clinical trial activity
9 trials · 13 clinical orgs · 0 marketing orgs
Phase 1
9
Phase 2
1
Phase 3
0
Phase 4
0
Earliest trial started Mar 29, 2018 (NCT04677088)
Timeline
2010s
- Jan 1, 2018
Earliest Phase 1 Sponsor(trial)
Indications
Studied for
- Carcinoma, Hepatocellular · Phase 1
- Carcinoma, Non-Small-Cell Lung · Phase 1
- Carcinoma, Ovarian Epithelial · Phase 1
- Colorectal Neoplasms · Phase 1
- Esophageal Neoplasms · Phase 1
- Leukemia, Myeloid, Acute · Early Phase 1
- Liposarcoma, Myxoid · Phase 1
- Lung Neoplasms · Phase 1
- Neoplasms · Phase 1
- Pancreatic Neoplasms · Phase 1
- Prostatic Neoplasms · Phase 1
- Sarcoma · Phase 1
- Sarcoma, Synovial · Phase 1
- Uterine Cervical Neoplasms · Phase 1/Phase 2
Mechanism of action
- Tumor antigensImmunity, passive
immunity, passive - tumor antigens
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06748872 | Phase 1 | Jul 1, 2025 | MediGene |
| NCT07014878 | Phase 1 | Jun 30, 2025 | Government of China |
| NCT06094842 | Phase 1 | Mar 1, 2024 | Bristol-Myers Squibb, University of Washington |
| NCT06043713 | Phase 1 | Jan 1, 2024 | Affini-T Therapeutics, Inc., University of Washington |
| NCT05648994 | Early Phase 1 (Phase 1) | Dec 31, 2022 | Fujian Medical University |
| NCT05357027 | Phase 1/Phase 2 (Phase 2) | Aug 10, 2022 | Fudan University, TCRCure Biopharma Corp. |
| NCT06904859 | Early Phase 1 (Phase 1) | Jan 1, 2019 | Shenzhen University |
| NCT03778814 | Phase 1 | Dec 1, 2018 | Guangzhou Medical University, Jinan University |
| NCT04677088 | Phase 1 | Mar 29, 2018 | Lion TCR Pte. Ltd., Sun Yat-Sen University |
Showing 9 of 9 trials
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Organizations
Research & Development (13)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| University of Washington | Academic/Hospital | 2 | 2 | 1 | 2024 |
| Affini-T Therapeutics, Inc. | For profit | 1 | 0 | 1 | 2024 |
| Bristol-Myers Squibb | For profit | 1 | 0 | 1 | 2024 |
| Fudan University | Academic/Hospital | 1 | 0 | 1 | 2022 |
| Fujian Medical University | Academic/Hospital | 1 | 1 | 1 | 2022 |
| Government of China | Government | 1 | 1 | 1 | 2025 |
| Guangzhou Medical University | Academic/Hospital | 1 | 1 | 1 | 2018 |
| Jinan University | Academic/Hospital | 1 | 0 | 1 | 2018 |
| Lion TCR Pte. Ltd. | For profit | 1 | 0 | 1 | 2018 |
| MediGene | For profit | 1 | 1 | 1 | 2025 |
| Shenzhen University | Academic/Hospital | 1 | 1 | 1 | 2019 |
| Sun Yat-Sen University | Academic/Hospital | 1 | 1 | 1 | 2018 |
| TCRCure Biopharma Corp. | For profit | 1 | 1 | 1 | 2022 |
13 organizations
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