fe203799

Peptideexperimental

Clinical trial activity

3 trials · 4 clinical orgs · 0 marketing orgs

Phase 1

Phase 2

Phase 3

Phase 4

Earliest trial started Feb 28, 2018 (NCT03408132)

Timeline

2010s

Jan 1, 2018
Earliest Phase 1 Sponsor(trial)

Indications

Studied for

Mechanism of action

Glucagon-like peptide 2 receptorAGONIST
Glucagon-like peptide 2 receptor agonist
- Glucagon-like peptide 2 receptor (GLP2R) ↗

Chemistry & pharmacology

Loading structure…

SMILES

CCCC[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(N)=O)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O

Mol. weight: 3765.24 g/mol
Chirality: Single Stereoisomer
Inorganic: No
Polymer: No
Multi-specific: No

Oral

Parenteral

Topical

Sources

ChEMBLCHEMBL4563522 ↗

Clinical trials

NCT ID	Phase	Start date	Sponsor(s)
NCT03417765	Phase 1/Phase 2 (Phase 2)	Apr 1, 2018	GLyPharma Therapeutic, Hôpital Maisonneuve Rosemont, Montréal, QC, Canada, JSS Medical Research Inc.
NCT03408132	Phase 1/Phase 2 (Phase 2)	Feb 28, 2018	GLyPharma Therapeutic, University of Copenhagen
NCT03415594	Phase 1/Phase 2 (Phase 2)	Feb 28, 2018	GLyPharma Therapeutic, University of Copenhagen

Showing 3 of 3 trials

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Organizations

Research & Development (4)

Organization	Org type	Trials	As lead sponsor	Phases	Earliest year
GLyPharma Therapeutic	For profit	3	3	1	2018
University of Copenhagen	Academic/Hospital	2	0	1	2018
Hôpital Maisonneuve Rosemont, Montréal, QC, Canada	Academic/Hospital	1	0	1	2018
JSS Medical Research Inc.	For profit	1	0	1	2018

4 organizations

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