oxazolidine
Small moleculeexperimental
Oxazolidine is a five-membered heterocycle ringwith the formula (CH2)3(NH)O.The O atom and NH groups are not mutually bonded, in contrast to isoxazolidine. Oxazolidines are derivatives of the parent oxazolidine owing to the presence of substituents on carbon and/or nitrogen. Oxazolines are unsaturated analogues of oxazolidines. — Wikipedia
Clinical trial activity
2 trials · 2 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
1
Phase 3
0
Phase 4
1
Earliest trial started Jan 1, 2017 (NCT03239015)
Timeline
2010s
- Jan 1, 2017
Earliest Phase 2 Sponsor(trial)
Indications
Studied for
Mechanism of action
- 50S ribosomal protein L2INHIBITOR
rplB inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
C1COCN1- Mol. weight
- 73.09 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- Yes
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaOxazolidine ↗
- ChEMBLCHEMBL4297314 ↗
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06712199 | Phase 4 | Jan 1, 2025 | Shandong Province Qianfoshan Hospital |
| NCT03239015 | Phase 2 | Jan 1, 2017 | Second Military Medical University |
Showing 2 of 2 trials
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Organizations
Research & Development (2)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Second Military Medical University | Government | 1 | 1 | 1 | 2017 |
| Shandong Province Qianfoshan Hospital | Academic/Hospital | 1 | 1 | 1 | 2025 |
2 organizations
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