tak-418
Small moleculeexperimental
Clinical trial activity
3 trials · 1 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
0
Phase 3
0
Phase 4
0
Earliest trial started Jul 21, 2017 (NCT03228433)
Timeline
2010s
- Jan 1, 2017
Earliest Phase 1 Sponsor(trial)
Indications
Studied for
Mechanism of action
- LSD1/CoREST complexINHIBITOR
LSD1/CoREST complex inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
O=C(NC1CCOCC1)C2=CSC(=C2)[C@@H]3C[C@H]3NCC4CC4- Mol. weight
- 320.45 g/mol
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- NCATSN9N6RK0CBN ↗
- ChEMBLCHEMBL4297835 ↗
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04202497 | Phase 1 | Dec 16, 2019 | Takeda |
| NCT03501069 | Phase 1 | May 15, 2018 | Takeda |
| NCT03228433 | Phase 1 | Jul 21, 2017 | Takeda |
Showing 3 of 3 trials
Page 1 / 1
Organizations
Research & Development (1)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Takeda | For profit | 3 | 3 | 1 | 2017 |
1 organizations
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