d-mannose
Small moleculeexperimental
Mannose is a sugar with the formula HOCH2(CHOH)4CHO, which sometimes is abbreviated Man. It is one of the monomers of the aldohexose series of carbohydrates. It is a C-2 epimer of glucose. Mannose is important in human metabolism, especially in the glycosylation of certain proteins. Several congenital disorders of glycosylation are associated with mutations in enzymes involved in mannose metabolism. — Wikipedia
Clinical trial activity
2 trials · 1 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
2
Phase 3
0
Phase 4
0
Earliest trial started Mar 31, 2015 (NCT03404869)
Timeline
2010s
- Jan 1, 2015
Earliest Phase 1 Sponsor(trial)
Indications
Mechanism of action
- Type 1 fimbiral adhesin FimHINHIBITOR
fimH inhibitor
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaMannose ↗
Also known as
- 6-o-phosphono-d-mannose
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03404856 | Phase 1/Phase 2 (Phase 2) | Oct 31, 2017 | Orpha Labs |
| NCT03404869 | Phase 1/Phase 2 (Phase 2) | Mar 31, 2015 | Orpha Labs |
Showing 2 of 2 trials
Page 1 / 1
Organizations
Research & Development (1)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Orpha Labs | For profit | 2 | 2 | 1 | 2015 |
1 organizations
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