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nsc-7571

Small moleculeexperimental

Aminacrine has long been known to be a potent frameshift mutagen in viruses and bacteria. It is one in a general class of aminoacridine dyes that bind to DNA and possess mutagenic activity. Aminacrine is used clinically as a topical antiseptic. A part from therapeutic use, aminacrine is also introduced as a matrix for negative mode matrix-assisted laser desorption/ionization (MALDI). — NCATS

Clinical trial activity

0 trials · 0 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0

Indications

Approved for

Studied for

Chemistry & pharmacology

Loading structure…

SMILES

Nc1c2ccccc2nc2ccccc12
Mol. weight
194.24 g/mol
Lipinski Ro5
Pass
Rule of 3
Yes
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • 9-acridinamine monohydrochloride
  • 9-aminoacridine
  • 9-aminoacridine monohydrochloride
  • aminacrin
  • aminacrine
  • aminacrine hcl
  • aminacrine hydrochloride
  • aminacrine hydrochloride
  • aminacrine hydrochloride
  • aminacrine hydrochloride
  • aminacrine hydrochloride
  • aminacrine hydrochloride
  • aminoacridine
  • aminoacridine
  • izoacridina
  • monacrin
  • nsc-7571