paveril
Small moleculeexperimental
Dimoxyline is the synthetic analogue of papaverine, Acute toxicity studies show it to be less toxic than papaverine. No analgesic action and no tolerance development in experimental animals by repeated administration. But Dimoxyline does not appear to be as potent as papaverine in comparable dosage. Dimoxyline is indicated for the treatment of patients with angina pectoris. Also, significant amount of benefit was claimed in patients with acute or chronic phlebitis, arterial thrombosis or embolism, Raynaud’s phenomena and early thromboangiitis obliterans or arteriosclerosis obliterans. Detected adverse events are: nausea or abdominal cramps. — NCATS
Clinical trial activity
0 trials · 0 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Chemistry & pharmacology
Loading structure…
SMILES
CCOC1=CC=C(CC2=C3C=C(OC)C(OC)=CC3=CC(C)=N2)C=C1OC- Mol. weight
- 367.4382 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- NCATS46X4C9TILS ↗
- ChEMBLCHEMBL2108950 ↗
- ChEMBLCHEMBL2105041 ↗
Also known as
- dimoxyline
- dioxyline
- dioxyline
- dioxyline phosphate
- dioxyline phosphate
- dioxyline phosphate
- paveril