valeramide
Aminopentamide is a potent antispasmodic agent. As a cholinergic blocking agent for smooth muscle, its action is similar to atropine. Aminopentamide hydrogen sulfate is marketed under the brand name Centrine indicated in the treatment of acute abdominal visceral spasm, pylorospasm or hypertrophic gastritis and associated nausea, vomiting and/or diarrhea of the dogs and cats. Centrine effectively reduces the tone and amplitude of colonic contractions to a greater degree and for a more extended period than does atropine. Centrine effects a reduction in gastric secretion, a decrease in gastric acidity and a marked decrease in gastric motility. Aminopentamide is a nonselective muscarinic cholinergic . — NCATS
Clinical trial activity
0 trials · 0 clinical orgs · 0 marketing orgs
Indications
Approved for
Chemistry & pharmacology
SMILES
CC(CC(C(N)=O)(C1=CC=CC=C1)C2=CC=CC=C2)N(C)C- Mol. weight
- 296.4067 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Racemic Mixture
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- NCATSIP1B47L61M ↗
- ChEMBLCHEMBL92915 ↗
Also known as
- aminopentamide
- aminopentamide sulfate
- centrine
- dimevamide
- dimevamide
- dimevamide
- dimevamide
- dimevamide
- valeramide