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iothiouracil

Small moleculeexperimental

IOTHIOURACIL, in a form of sodium salt, was used as an antithyroid agent in the treatment of hyperthyroidism. It is selectively incorporated into the melanin pigment of melanomas during biosynthesis by serving as false melanin precursors. Radiolabelled (125I) IOTHIOURACIL may be used as a radiopharmaceutical for diagnosis and therapy of melanotic melanomas. — NCATS

Clinical trial activity

0 trials · 0 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0

Indications

Approved for

Chemistry & pharmacology

Loading structure…

SMILES

IC1=CNC(=S)NC1=O
Mol. weight
254.049 g/mol
Lipinski Ro5
Pass
Rule of 3
Yes
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • 5-iodo-2-thiouracil
  • iodothiouracil
  • iodothiouracil
  • iodothiouracil
  • iodothiouracil
  • iothiouracil