Amcasertib

Small moleculeexperimental

Clinical trial activity

10 trials · 3 clinical orgs · 0 marketing orgs

Phase 1
6
Phase 2
8
Phase 3
0
Phase 4
0

Earliest trial started Feb 1, 2012 (NCT01781455)

Timeline

2010s

  1. Jan 1, 2012

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2015

    Earliest Phase 2 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(-c4csc(-c5ccccc5)n4)cc32)c1C
Mol. weight
539.71 g/mol
Lipinski Ro5
2 violation(s)
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • bbi503
  • bbi503

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT05784779Phase 1/Phase 2 (Phase 2)Feb 28, 20231Globe Biomedical Co., Ltd.
NCT02232620Phase 2Mar 13, 2017Boston Biomedical
NCT02232646Phase 2Jan 1, 2017Boston Biomedical
NCT02483247Phase 1/Phase 2 (Phase 2)Sep 1, 2015Boston Biomedical
NCT02432690Phase 2Jun 1, 2015Boston Biomedical
NCT02432326Phase 1Apr 1, 2015Boston Biomedical
NCT02354898Phase 1Mar 1, 2015Sumitomo Dainippon
NCT02232633Phase 2Feb 1, 2015Boston Biomedical
NCT02279719Phase 1/Phase 2 (Phase 2)Dec 1, 2014Boston Biomedical
NCT01781455Phase 1/Phase 2 (Phase 2)Feb 1, 2012Boston Biomedical
Showing 10 of 10 trials
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Organizations

Research & Development (3)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Boston BiomedicalFor profit8822012
1Globe Biomedical Co., Ltd.For profit1112023
Sumitomo DainipponFor profit1112015
3 organizations
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