padimate o
Small moleculeexperimental
Padimate O is an organic compound related to the water-soluble compound PABA (4-aminobenzoic acid) that is used as an ingredient in some sunscreens. this chemical releases free radicals, damages DNA, has estrogenic activity, and causes allergic reactions in some people. Maximum FDA-approved concentration - 8%. Range of protection - UVB. — NCATS
Clinical trial activity
1 trials · 1 clinical orgs · 0 marketing orgs
Phase 1
1
Phase 2
0
Phase 3
0
Phase 4
0
Earliest trial started Aug 1, 2016 (NCT02668536)
Timeline
2010s
- Jan 1, 2016
Earliest Phase 1 Sponsor(trial)
Indications
Approved for
Studied for
Mechanism of action
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
Loading structure…
SMILES
CCCCC(CC)COC(=O)C1=CC=C(C=C1)N(C)C- Mol. weight
- 277.4018 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Racemic Mixture
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- NCATSZ11006CMUZ ↗
- ChEMBLCHEMBL1323699 ↗
Also known as
- 2-ethylhexyl 4-(dimethylamino)benzoate
- 2-ethylhexyl-p-dimethylaminobenzoate
- 4-n,n'-dimethylamino-benzoic acid, 2-ethylhexyl ester
- arlatone 507
- arlatone uvb
- arlatone uvb
- climacel
- escalol 507
- escalol 507
- escalol 507
- octyl dimethyl paba
- padimate
- padimate
- padimate o
- padimate o
- padimate o
- padimate o
- padimate o
- padimate o
- padimate o
- padimate-o
- padimate-o
- padimate-o
- spectraban 25
- spectraban 4
- spectraban ultra
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT02668536 | Phase 1 | Aug 1, 2016 | Yale University |
Showing 1 of 1 trials
Page 1 / 1
Organizations
Research & Development (1)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Yale University | Academic/Hospital | 1 | 1 | 1 | 2016 |
1 organizations
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