uric acid
Small moleculeexperimental
Uric acid is a heterocyclic compound of carbon, nitrogen, oxygen, and hydrogen with the formula C5H4N4O3. It forms ions and salts known as urates and acid urates, such as ammonium acid urate. Uric acid is a product of the metabolic breakdown of purine nucleotides, and it is a normal component of urine. High blood concentrations of uric acid can lead to gout and are associated with other medical conditions, including diabetes and the formation of ammonium acid urate kidney stones. — Wikipedia
Clinical trial activity
2 trials · 3 clinical orgs · 0 marketing orgs
Phase 1
1
Phase 2
0
Phase 3
1
Phase 4
0
Earliest trial started Mar 31, 2009 (NCT01323335)
Timeline
Indications
Mechanism of action
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
Loading structure…
SMILES
Oc1nc(O)c2nc(O)[nH]c2n1- Mol. weight
- 168.11 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaUric acid ↗
- ChEMBLCHEMBL792 ↗
Also known as
- 2,6,8-trihydroxypurine
- 2,6,8-trihydroxypurine
- 7,9-dihydro-1h-purine-2,6,8(3h)-trione
- 7,9-dihydro-1h-purine-2,6,8(3h)-trione
- urate
- urate
- uric acid
- uric acid
- uric acid
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT00860366 | Phase 2/Phase 3 (Phase 3) | Jun 1, 2011 | Fundacion Clinic per a la Recerca Biomédica, Universidad Carlos III Madrid |
| NCT01323335 | Phase 1 | Mar 31, 2009 | National Institute on Aging (NIA) |
Showing 2 of 2 trials
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Organizations
Research & Development (3)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Fundacion Clinic per a la Recerca Biomédica | Academic/Hospital | 1 | 1 | 1 | 2011 |
| National Institute on Aging (NIA) | Government | 1 | 1 | 1 | 2009 |
| Universidad Carlos III Madrid | Academic/Hospital | 1 | 0 | 1 | 2011 |
3 organizations
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