methylsulfonylmethane

Small moleculeexperimental

Dimethyl sulfone (DMSO2) is an organosulfur compound with the formula (CH3)2SO2. It is also known by several other names including methyl sulfone and (especially in alternative medicine) methylsulfonylmethane (MSM). This colorless solid features the sulfonyl functional group and is the simplest of the sulfones. It is relatively inert chemically and is able to resist decomposition at elevated temperatures. It occurs naturally in some primitive plants, is present in small amounts in many foods and beverages, and is marketed (under the MSM name) as a dietary supplement. It is sometimes used as a cutting agent for illicitly manufactured methamphetamine. It is also commonly found in the atmosphere above marine areas, where it is used as a carbon source by the airborne bacteria Afipia. Oxidation of dimethyl sulfoxide produces the sulfone, both under laboratory conditions and metabolically. — Wikipedia

Clinical trial activity

6 trials · 9 clinical orgs · 0 marketing orgs

Phase 1
1
Phase 2
1
Phase 3
1
Phase 4
0

Earliest trial started Aug 21, 2010 (NCT01188213)

Timeline

2010s

  1. Jan 1, 2012

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2015

    Earliest Phase 3 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • methane, sulfonylbis-
  • methyl sulfone
  • methyl sulfonmethane
  • methylsulfonylmethane
  • methylsulfonylmethane
  • methylsulfonylmethane

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT04664712N/ASep 11, 2019ASL Bari, University of Bari
NCT03747198N/AFeb 1, 2019Bergstrom Nutrition, University of California, Davis
NCT03716791N/AJan 31, 2019Washington State University
NCT02268305Phase 3Feb 1, 2015United States Air Force
NCT01836757Phase 1Sep 1, 2012Aristotle University of Thessaloniki, G.Papanikolaou Research Group
NCT01188213N/AAug 21, 2010Tel Aviv University
Showing 6 of 6 trials
Page 1 / 1

Organizations

Research & Development (9)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Aristotle University of ThessalonikiAcademic/Hospital1012012
ASL BariAcademic/Hospital1112019
Bergstrom NutritionFor profit1012019
G.Papanikolaou Research GroupAcademic/Hospital1112012
Tel Aviv UniversityAcademic/Hospital1112010
United States Air ForceGovernment1112015
University of BariAcademic/Hospital1012019
University of California, DavisAcademic/Hospital1112019
Washington State UniversityAcademic/Hospital1112019
9 organizations
Page 1 / 1