l-cystine

Small moleculeexperimental

Cystine is the oxidized dimer form of the amino acid cysteine. Cystine serves two biological functions, a site of redox reactions and a mechanical linkage that allows proteins to retain their 3-dimensional structure. It is common in many foods such as eggs, meat, dairy products, and whole grains as well as skin, horns and hair. Human hair and skin contain approximately 10–14% cystine by mass. Cysteine supplements are sometimes marketed as anti-aging products with claims of improved skin elasticity. Cysteine is more easily absorbed by the body than cystine, so most supplements contain cysteine rather than cystine. N-acetyl-cysteine (NAC) is better absorbed than other cysteine or cystine supplements. — NCATS

Clinical trial activity

1 trials · 2 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0

Earliest trial started Apr 23, 2018 (NCT03337360)

Timeline

No events for the selected filters.

Chemistry & pharmacology

Loading structure…

SMILES

N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O
Mol. weight
240.3 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • cystine
  • cystine
  • cystine
  • cystine
  • cystine
  • cystine
  • cystine
  • l-alpha-diamino-beta-dithiolactic acid
  • l-alpha-diamino-beta-dithiolactic acid
  • l-cystine
  • l-cystine
  • l-cystine
  • l-dicysteine
  • l-dicysteine
  • (r,r)-3,3'-dithiobis(2-aminopropanoic acid)
  • (r,r)-3,3'-dithiobis(2-aminopropanoic acid)
  • β,β'-dithiodialanine
  • β,β'-dithiodialanine

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT03337360N/AApr 23, 2018Goodlife Fertility B.V., Radboud University
Showing 1 of 1 trials
Page 1 / 1

Organizations

Research & Development (2)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Goodlife Fertility B.V.Academic/Hospital1012018
Radboud UniversityAcademic/Hospital1112018
2 organizations
Page 1 / 1