l-cystine
Cystine is the oxidized dimer form of the amino acid cysteine. Cystine serves two biological functions, a site of redox reactions and a mechanical linkage that allows proteins to retain their 3-dimensional structure. It is common in many foods such as eggs, meat, dairy products, and whole grains as well as skin, horns and hair. Human hair and skin contain approximately 10–14% cystine by mass. Cysteine supplements are sometimes marketed as anti-aging products with claims of improved skin elasticity. Cysteine is more easily absorbed by the body than cystine, so most supplements contain cysteine rather than cystine. N-acetyl-cysteine (NAC) is better absorbed than other cysteine or cystine supplements. — NCATS
Clinical trial activity
1 trials · 2 clinical orgs · 0 marketing orgs
Earliest trial started Apr 23, 2018 (NCT03337360)
Timeline
No events for the selected filters.
Chemistry & pharmacology
SMILES
N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O- Mol. weight
- 240.3 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaCystine ↗
- NCATS48TCX9A1VT ↗
- ChEMBLCHEMBL590540 ↗
Also known as
- cystine
- cystine
- cystine
- cystine
- cystine
- cystine
- cystine
- l-alpha-diamino-beta-dithiolactic acid
- l-alpha-diamino-beta-dithiolactic acid
- l-cystine
- l-cystine
- l-cystine
- l-dicysteine
- l-dicysteine
- (r,r)-3,3'-dithiobis(2-aminopropanoic acid)
- (r,r)-3,3'-dithiobis(2-aminopropanoic acid)
- β,β'-dithiodialanine
- β,β'-dithiodialanine
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03337360 | N/A | Apr 23, 2018 | Goodlife Fertility B.V., Radboud University |
Organizations
Research & Development (2)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Goodlife Fertility B.V. | Academic/Hospital | 1 | 0 | 1 | 2018 |
| Radboud University | Academic/Hospital | 1 | 1 | 1 | 2018 |