gramicidin d
Small moleculeapproved
Approved
Jun 1, 1949
Clinical trial activity
1 trials · 1 clinical orgs · 1 marketing orgs
Phase 1
0
Phase 2
1
Phase 3
1
Phase 4
0
Earliest trial started Sep 1, 2007 (NCT00534391)
Timeline
1940s
- Jun 1, 1949
Burroughs Wellcome — Earliest FDA Approval
- Jun 1, 1949
Burroughs Wellcome — NDA Organization
2000s
- Jan 1, 2007
Earliest Phase 3 Sponsor(trial)
Indications
Studied for
Mechanism of action
- Cell membraneDISRUPTING AGENT
Cell membrane disrupting agent
Approval history
- approvedJun 1, 1949
Chemistry & pharmacology
Loading structure…
SMILES
CC(C)C[C@@H](NC(=O)CNC(=O)[C@@H](NC=O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCO)C(C)C)C(C)C)C(C)C- Mol. weight
- 1811.25 g/mol
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Delivery
- Topical
- Availability
- Prescription Only
Oral
No
Parenteral
No
Topical
Yes
Sources
- ChEMBLCHEMBL557217 ↗
- ChEMBLCHEMBL1201469 ↗
Also known as
- bacillus brevis gramicidin d
- bacillus brevis gramicidin d
- gramicidin
- gramicidin
- gramicidin
- gramicidin
- gramicidin
- gramicidin
- gramicidin
- gramicidin
- gramicidin
- gramicidin d
- gramicidin d
- gramicidin d
- gramicidin d
- gramicidin dubos
- gramicidine
- gramicidine
- gramicidine
- gramicidins
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT00534391 | Phase 3 | Sep 1, 2007 | Chulalongkorn University |
Showing 1 of 1 trials
Page 1 / 1
Organizations
Research & Development (1)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Chulalongkorn University | Academic/Hospital | 1 | 1 | 1 | 2007 |
1 organizations
Page 1 / 1
Marketing (1)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| Burroughs Wellcome | For profit | NDA | Jun 1, 1949 |