levodropropizine
Small moleculeexperimental
Levodropropizine is a cough suppressant. It is the levo isomer of dropropizine. It acts as a peripheral antitussive, with no action in the central nervous system. It does not cause side effects such as constipation or respiratory depression which can be produced by opioid antitussives such as codeine and its derivatives. — Wikipedia
Clinical trial activity
4 trials · 12 clinical orgs · 0 marketing orgs
Phase 1
1
Phase 2
3
Phase 3
3
Phase 4
0
Earliest trial started May 1, 2010 (NCT01416480)
Timeline
Indications
Mechanism of action
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
Loading structure…
SMILES
OC[C@@H](O)CN1CCN(c2ccccc2)CC1- Mol. weight
- 236.31 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaLevodropropizine ↗
- ChEMBLCHEMBL1288810 ↗
Also known as
- (-)-dropropizine
- levodropropizine
- levodropropizine
- levodropropizine
- levodropropizine
- levodropropizine
- levodropropizine
- levodropropizine
- levodropropizine
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03489837 | Phase 3 | Jan 31, 2017 | Hyundai |
| NCT03837938 | Phase 3 | Nov 9, 2016 | Dompe Pharmaceuticals |
| NCT01573663 | Phase 1 | Feb 1, 2012 | Hanmi Pharmaceutical, Sungkyunkwan University |
| NCT01416480 | Phase 3 | May 1, 2010 | Ahn-Gook Pharmaceuticals Co.,Ltd, Catholic University of Korea, Chung-Ang University, Ewha Womans University, Hallym University, Inje University, Soonchunhyang University, Yeungnam University |
Showing 4 of 4 trials
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Organizations
Research & Development (12)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Ahn-Gook Pharmaceuticals Co.,Ltd | For profit | 1 | 1 | 1 | 2010 |
| Catholic University of Korea | Academic/Hospital | 1 | 0 | 1 | 2010 |
| Chung-Ang University | Academic/Hospital | 1 | 0 | 1 | 2010 |
| Dompe Pharmaceuticals | For profit | 1 | 1 | 1 | 2016 |
| Ewha Womans University | Academic/Hospital | 1 | 0 | 1 | 2010 |
| Hallym University | Academic/Hospital | 1 | 0 | 1 | 2010 |
| Hanmi Pharmaceutical | For profit | 1 | 1 | 1 | 2012 |
| Hyundai | For profit | 1 | 1 | 1 | 2017 |
| Inje University | Academic/Hospital | 1 | 0 | 1 | 2010 |
| Soonchunhyang University | Academic/Hospital | 1 | 0 | 1 | 2010 |
| Sungkyunkwan University | Academic/Hospital | 1 | 0 | 1 | 2012 |
| Yeungnam University | Academic/Hospital | 1 | 0 | 1 | 2010 |
12 organizations
Page 1 / 1