dropropizine

Small moleculeexperimental

Dropropizine is a cough suppressant that is sold in Germany, Central America, South America, and some African countries such as Congo. It is sold as suppositories, tablets, and syrup. It is used to stop a cough caused by allergies or a cold. — Wikipedia

Clinical trial activity

7 trials · 7 clinical orgs · 0 marketing orgs

Phase 1
1
Phase 2
5
Phase 3
5
Phase 4
0

Earliest trial started Apr 1, 2003 (NCT00112229)

Timeline

2000s

  1. Jan 1, 2003

    Earliest Phase 1 Sponsor(trial)

2010s

  1. Jan 1, 2011

    Earliest Phase 3 Sponsor(trial)

Indications

Mechanism of action

  • Unspecified targetUnclear

    unclear

Chemistry & pharmacology

Loading structure…

SMILES

OCC(O)CN1CCN(c2ccccc2)CC1
Mol. weight
236.32 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Racemic Mixture
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • catabex
  • df 526
  • df-526
  • dipropizine
  • dipropizine
  • dipropizine, (s)-isomer
  • ditustat
  • dopropizin
  • dropropizine
  • dropropizine
  • dropropizine
  • dropropizine
  • dropropizine
  • dropropizine
  • dropropizine
  • levotuss
  • tautoss
  • ucb-1967
  • ucb-1967
  • zyplo

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT01393561Phase 3Jul 1, 2014Ache Laboratorios Farmaceuticos S.A.
NCT01257061Phase 3Sep 1, 2012EMS S/A, Medcin Instituto da Pele
NCT01872598Phase 3Jan 1, 2012AB Science
NCT01177852Phase 3Oct 1, 2011Ache Laboratorios Farmaceuticos S.A.
NCT01199497Phase 3Aug 1, 2011Ache Laboratorios Farmaceuticos S.A.
NCT01074190N/AJan 1, 2010Northwestern University
NCT00112229Phase 1Apr 1, 2003Ludwig Institute for Cancer Research, University of Lausanne
Showing 7 of 7 trials
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Organizations

Research & Development (7)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Ache Laboratorios Farmaceuticos S.A.For profit3312011
AB ScienceFor profit1112012
EMS S/AFor profit1112012
Ludwig Institute for Cancer ResearchAcademic/Hospital1012003
Medcin Instituto da PeleAcademic/Hospital1012012
Northwestern UniversityAcademic/Hospital1112010
University of LausanneAcademic/Hospital1112003
7 organizations
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