fibrinolysin, human
Biologicalapproved
Approved
Apr 1, 1964
Clinical trial activity
6 trials · 7 clinical orgs · 2 marketing orgs
Phase 1
3
Phase 2
5
Phase 3
1
Phase 4
0
Earliest trial started Apr 1, 2006 (NCT00348439)
Timeline
Indications
Approved for
Mechanism of action
Combination products
elase-chloromycetin
Approval history
- approvedApr 1, 1964
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Delivery
- Topical
- Availability
- Discontinued
Oral
No
Parenteral
No
Topical
Yes
Sources
- NCATSD60E3WIF5Y ↗
- ChEMBLCHEMBL1201505 ↗
- NCATSA4028U842W ↗
Also known as
- actase
- fibrinolysin
- fibrinolysin
- fibrinolysin
- fibrinolysin (human)
- fibrinolysin (human)
- fibrinolysin, human
- fibrinolysin, human
- plasmin
- plasmin
- plasmin
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04236739 | Phase 3 | Jul 23, 2019 | Utrecht University, ZonMw: The Netherlands Organisation for Health Research and Development |
| NCT01222117 | Phase 2 | Dec 1, 2010 | Grifols |
| NCT01014975 | Phase 1/Phase 2 (Phase 2) | Nov 1, 2009 | Grifols, Melbourne Health, University of California, Los Angeles |
| NCT00418483 | Phase 1 | Mar 1, 2007 | Grifols, Jobst Vascular Center |
| NCT00347646 | Phase 1/Phase 2 (Phase 2) | Sep 1, 2006 | Bausch & Lomb |
| NCT00348439 | Phase 2 | Apr 1, 2006 | Bausch & Lomb |
Showing 6 of 6 trials
Page 1 / 1
Organizations
Research & Development (7)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Grifols | For profit | 3 | 3 | 2 | 2007 |
| Bausch & Lomb | For profit | 2 | 2 | 1 | 2006 |
| Jobst Vascular Center | Academic/Hospital | 1 | 0 | 1 | 2007 |
| Melbourne Health | Academic/Hospital | 1 | 0 | 1 | 2009 |
| University of California, Los Angeles | Academic/Hospital | 1 | 0 | 1 | 2009 |
| Utrecht University | Academic/Hospital | 1 | 1 | 1 | 2019 |
| ZonMw: The Netherlands Organisation for Health Research and Development | Academic/Hospital | 1 | 0 | 1 | 2019 |
7 organizations
Page 1 / 1
Marketing (3)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| Parke-Davis | For profit | NDA2 | Apr 1, 1964 |
| Pfizer | For profit | NDA2 | Apr 1, 1964 |
| Pfizer | For profit | NDA | Apr 1, 1964 |