sodium chromate cr-51
Trade name: chromitope sodium
Approved
Dec 23, 1971
Chromate ion CR-51 is a radioactive chromium 51 in the form of sterile, nonpyrogenic aqueous solution of sodium chromate. It is a diagnostic radiopharmaceutical for intravenous administration. This agent provides Chromium 51 decays by electron capture and gamma emission with a physical half-life of 27.7 days. It is indicated for use in determining red blood cell volume or mass, studying red blood cell survival time (in conditions such as hemolytic anemia), and evaluating blood loss. No adverse reactions specifically attributable to Chromate ion CR-51 injection have been reported. — NCATS
Clinical trial activity
0 trials · 0 clinical orgs · 2 marketing orgs
Timeline
1970s
- Dec 23, 1971
Earliest FDA Approval
- Dec 23, 1971
Curium Pharma — NDA Secondary Org
- Dec 27, 1971
Bracco — First NDA Organization
- Dec 27, 1971
Bracco — NDA Secondary Org
- Dec 27, 1971
Bracco — NDA Organization
Indications
Mechanism of action
- Hemoglobin alpha subunitBINDING AGENT
Hemoglobin alpha subunit binding agent
- Unspecified targetOTHER
Radiopharmaceutical
Approval history
- approvedDec 23, 1971
Chemistry & pharmacology
SMILES
[O-][51Cr]([O-])(=O)=O- Mol. weight
- 114.9424 g/mol
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Delivery
- Parenteral
- Availability
- Discontinued
- Imaging
- 51-chromium
Oral
No
Parenteral
Yes
Topical
No
Sources
- NCATSSVU4HTP02M ↗
- ChEMBLCHEMBL2096634 ↗
- ChEMBLCHEMBL1201450 ↗
Also known as
- 51cr
- 51cr
- chromitope sodium
- chromitope sodium
- chromitope sodium
- chromitope sodium
- chromitope sodium
- chromium sodium oxide (crna2o4)
- rachromate
- rachromate
- sodium chromate
- sodium chromate (51cr)
- sodium chromate (51cr)
- sodium chromate (51cr)
- sodium chromate (51cr) injection
- sodium chromate cr 51
- sodium chromate cr 51
- sodium chromate cr-51
- sodium chromate cr-51
- sodium chromate cr-51
- sodium chromate cr-51
- sodium chromate(vi)
- sodium chromate(vi), 51cr-labeled cpd
- sodium chromate(vi), decahydrate
- sodium chromate(vi), tetrahydrate
- sodium radiochromate
- sodium radiochromate
Organizations
Marketing (3)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| Bracco | For profit | NDA2 | Dec 27, 1971 |
| Bracco | For profit | NDA | Dec 27, 1971 |
| Curium Pharma | For profit | NDA2 | Dec 23, 1971 |