serratiopeptidase
Animal productexperimental
Serratiopeptidase is a proteolytic enzyme (protease) produced by enterobacterium Serratia sp. E-15, now known as Serratia marcescens ATCC 21074. This microorganism was originally isolated in the late 1960s from silkworm intestine. Serratiopeptidase is present in the silkworm intestine and allows the emerging moth to dissolve its cocoon. Serratiopeptase is produced by purification from culture of Serratia E-15 bacteria. It is a member of the Peptidase M10B (Matrixin) family. — Wikipedia
Clinical trial activity
4 trials · 5 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
3
Phase 3
2
Phase 4
1
Earliest trial started Mar 1, 2012 (NCT02862223)
Timeline
Indications
Approved for
Mechanism of action
- Unspecified targetOTHER
Proteolytic enzyme
Proteolytic enzyme - anti-inflammatory, fibrinolytic and mucolytic effects
- UnclearUnclear
Unclear unclear
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaSerratiopeptidase ↗
- ChEMBLCHEMBL2108880 ↗
Also known as
- aniflazym
- danzen
- dasen
- serodase
- serrapeptase
- serrapeptase
- serrapeptase
- serrapeptase
- serratiopeptidase
- serratiopeptidase
- serratiopeptidase
- serrepeptase
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07304882 | Phase 3 | Nov 30, 2023 | University of Science and Technology, Yemen |
| NCT07146997 | Phase 3 | Nov 23, 2023 | HITEC-Institute of Medical Sciences |
| NCT02493179 | Phase 4 | Jun 1, 2015 | Hayat Pharmaceutical Co. PLC |
| NCT02862223 | Phase 2 | Mar 1, 2012 | Arthur Andrew Medical, KGK Science Inc. |
Showing 4 of 4 trials
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Organizations
Research & Development (5)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Arthur Andrew Medical | Academic/Hospital | 1 | 0 | 1 | 2012 |
| Hayat Pharmaceutical Co. PLC | For profit | 1 | 1 | 1 | 2015 |
| HITEC-Institute of Medical Sciences | Academic/Hospital | 1 | 1 | 1 | 2023 |
| KGK Science Inc. | For profit | 1 | 1 | 1 | 2012 |
| University of Science and Technology, Yemen | Academic/Hospital | 1 | 1 | 1 | 2023 |
5 organizations
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