proxibarbal
Small moleculeexperimental
Clinical trial activity
0 trials · 0 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Mechanism of action
- Monoamine oxidase AACTIVATOR
MAOA activator
Proxibarbal is a non-sedative barbiturate with a specific anti-serotonin and anti-histamine effect, due to enzyme induction of serotoninase and histaminase. Its lack of unpleasant side-effects permits its use for the preventive treatment of migraine.
- Diamine oxidaseACTIVATOR
AOC1 activator
Proxibarbal is a non-sedative barbiturate with a specific anti-serotonin and anti-histamine effect, due to enzyme induction of serotoninase and histaminase. Its lack of unpleasant side-effects permits its use for the preventive treatment of migraine.
Chemistry & pharmacology
Loading structure…
SMILES
C=CCC1(CC(C)O)C(=O)NC(=O)NC1=O- Mol. weight
- 226.23 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Racemic Mixture
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL2105233 ↗
Also known as
- 2,4,6(1h,3h,5h)-pyrimidinetrione, 5-(2-hydroxypropyl)-5-(2-propenyl)-
- axeen
- centralagol
- centralgol
- hydroxydial
- ipronal
- ipronal
- proxibarbal
- proxibarbal
- proxibarbal
- proxibarbal
- proxibarbal
- proxibarbal
- proxibarbal
- proxibarbital
- proxybarbital
- vasalgin