pipamazine
Small moleculeexperimental
PIPAMAZINE is a drug of the phenothiazine class formerly used as an antiemetic. It was eventually withdrawn from the US market in 1969, after reports of hepatotoxicity (liver injury). — NCATS
Clinical trial activity
0 trials · 0 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Mechanism of action
- Unspecified targetOTHER
Unknown
It is a tranquilizer with a separation of the anti-emetic and tranquilizing qualities. Its action is on the medullary chemoreceptor centre.
Chemistry & pharmacology
Loading structure…
SMILES
NC(=O)C1CCN(CCCN2C3=CC=CC=C3SC4=CC=C(Cl)C=C24)CC1- Mol. weight
- 401.953 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaPipamazine ↗
- NCATS653552FH1N ↗
- ChEMBLCHEMBL1909072 ↗
Also known as
- mornidine
- nausidol
- nometine
- pipamazine
- pipamazine
- pipamazine
- pipamazine
- pipamazine
- pipamazine