horse chestnut
Botanicalexperimental
The genus Aesculus, with notable species including buckeye and horse chestnut, comprises 13–19 species of flowering plants in the family Sapindaceae. They are trees and shrubs native to the temperate Northern Hemisphere, with six species native to North America and seven to 13 species native to Eurasia. Several hybrids occur. Aesculus exhibits a classical Arcto-Tertiary distribution. — Wikipedia
Clinical trial activity
9 trials · 10 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
5
Phase 3
0
Phase 4
3
Earliest trial started May 1, 2002 (NCT00213928)
Timeline
2000s
- Jan 1, 2002
Earliest Phase 2 Sponsor(trial)
Indications
Approved for
Mechanism of action
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaAesculus ↗
- ChEMBLCHEMBL2109073 ↗
Also known as
- hippocastani semen
- hippocastanum
- hippocastanum
- horse chestnut
- horse chestnut
- horse chestnut, buckeye
- horse chestnut seed extract
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06872034 | N/A | Apr 16, 2025 | Peking University |
| NCT06329167 | Phase 4 | Mar 25, 2024 | Jinlin University |
| NCT06579482 | Phase 4 | Nov 6, 2023 | Fundação Educacional Serra dos Órgãos |
| NCT04503746 | Phase 2 | Jul 16, 2020 | AngioLab, Inc. |
| NCT04035317 | Phase 2 | Oct 31, 2017 | Casa Espirita Terra de Ismael, University of Ribeirao Preto |
| NCT03335683 | Phase 4 | Jan 7, 2016 | University of Campania Luigi Vanvitelli, University of Messina |
| NCT02483962 | Phase 2 | Feb 28, 2015 | University of Johannesburg |
| NCT02498327 | Phase 2 | Jan 31, 2015 | University of Johannesburg |
| NCT00213928 | Phase 2 | May 1, 2002 | University of Wisconsin |
Showing 9 of 9 trials
Page 1 / 1
Organizations
Research & Development (10)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| University of Johannesburg | Academic/Hospital | 2 | 2 | 1 | 2015 |
| AngioLab, Inc. | For profit | 1 | 1 | 1 | 2020 |
| Casa Espirita Terra de Ismael | Academic/Hospital | 1 | 1 | 1 | 2017 |
| Fundação Educacional Serra dos Órgãos | Academic/Hospital | 1 | 1 | 1 | 2023 |
| Jinlin University | Academic/Hospital | 1 | 1 | 1 | 2024 |
| Peking University | Academic/Hospital | 1 | 1 | 1 | 2025 |
| University of Campania Luigi Vanvitelli | Academic/Hospital | 1 | 1 | 1 | 2016 |
| University of Messina | Academic/Hospital | 1 | 0 | 1 | 2016 |
| University of Ribeirao Preto | Academic/Hospital | 1 | 0 | 1 | 2017 |
| University of Wisconsin | Academic/Hospital | 1 | 1 | 1 | 2002 |
10 organizations
Page 1 / 1