methoxyverapamil
Small moleculeexperimental
Gallopamil (INN) is an L-type calcium channel blocker that is an analog of verapamil. It is used in the treatment of abnormal heart rhythms. — Wikipedia
Clinical trial activity
1 trials · 1 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
1
Phase 3
0
Phase 4
0
Earliest trial started Dec 1, 2009 (NCT00896428)
Timeline
2000s
- Jan 1, 2009
Earliest Phase 2 Sponsor(trial)
Indications
Studied for
Mechanism of action
- Cytochrome P450 3A43INHIBITOR
CYP3A43 inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
COc1ccc(CCN(C)CCCC(C#N)(c2cc(OC)c(OC)c(OC)c2)C(C)C)cc1OC- Mol. weight
- 484.64 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Racemic Mixture
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaGallopamil ↗
- ChEMBLCHEMBL523367 ↗
- ChEMBLCHEMBL51149 ↗
Also known as
- gallopamil
- gallopamil
- gallopamil
- gallopamil
- gallopamil
- gallopamil
- gallopamil
- gallopamil hcl
- gallopamil hydrochloride
- methoxyverapamil
- methoxyverapamil
- methoxyverapamil
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT00896428 | Phase 2 | Dec 1, 2009 | University of Bordeaux |
Showing 1 of 1 trials
Page 1 / 1
Organizations
Research & Development (1)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| University of Bordeaux | Academic/Hospital | 1 | 1 | 1 | 2009 |
1 organizations
Page 1 / 1