evt-101
Small moleculeexperimental
Clinical trial activity
0 trials · 0 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Mechanism of action
- Glutamate NMDA receptor; GRIN1/GRIN2BANTAGONIST
Glutamate NMDA receptor; GRIN1/GRIN2B antagonist
Non-competitive antagonist, negative modulator.
GRIN2B selective.
Binds to ifenprodil site on N-terminal domain.
Chemistry & pharmacology
Loading structure…
SMILES
Cc1nccn1Cc1cc(-c2ccc(F)c(C(F)F)c2)cnn1- Mol. weight
- 318.3 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL3545350 ↗
- ChEMBLCHEMBL3545349 ↗
Also known as
- evt-101
- evt-101