domiphen
Small moleculeexperimental
Domiphen bromide it is used for the treatment of Acute Infectious Dental Diseases. Domiphen bromide is a quaternary antiseptic with actions and uses similar to those of cationic surfactants. Domiphen bromide has potent activity on blockade of human ether-a-go-go related gene (HERG) channels. — NCATS
Clinical trial activity
1 trials · 1 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
1
Phase 3
0
Phase 4
0
Earliest trial started Sep 30, 2021 (NCT04813822)
Timeline
2020s
- Jan 1, 2021
Earliest Phase 2 Sponsor(trial)
Indications
Approved for
Studied for
Mechanism of action
- Unspecified targetSurfactant
surfactant
Chemistry & pharmacology
Loading structure…
SMILES
CCCCCCCCCCCC[N+](C)(C)CCOc1ccccc1- Mol. weight
- 334.57 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL1187011 ↗
- NCATS4AZL56CU0F ↗
- ChEMBLCHEMBL486696 ↗
Also known as
- 1-dodecanaminium, n,n-dimethyl-n-(2-phenoxyethyl)
- 1-dodecanaminium, n,n-dimethyl-n-(2-phenoxyethyl)
- (beta-phenoxyethyl)dimethyldodecylammonium
- (beta-phenoxyethyl)dimethyldodecylammonium
- dodecyldimethyl(2-phenoxyethyl)ammonium
- dodecyldimethyl(2-phenoxyethyl)ammonium
- dodecyldimethyl(2-phenoxyethyl)ammonium
- domiphen
- domiphen
- domiphen
- domiphen
- domiphen
- domiphen
- domiphen bromide
- domiphen bromide
- domiphen bromide
- domiphen bromide
- domiphen cation
- domiphen cation
- domiphen chloride
- domiphen chloride
- domiphen chloride
- domiphen chloride
- domiphen chloride
- domiphen hydroxide
- domiphen hydroxide
- domiphen ion
- domiphen ion
- phenododecinium
- phenododecinium
- phenododecinium bromide
- phenododecinium bromide
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04813822 | Phase 2 | Sep 30, 2021 | Aesculap AG |
Showing 1 of 1 trials
Page 1 / 1
Organizations
Research & Development (1)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Aesculap AG | For profit | 1 | 1 | 1 | 2021 |
1 organizations
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