ditetradecanoylphosphatidylcholine

Small moleculeexperimental

1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE (dimyristoyl phosphatidylcholine, DMPC) is a synthetic phospholipid used in liposomes and lipid bilayers for the study of biological membranes. DMPC is a frequently studied artificial lipid because it undergoes a phase transition at a convenient temperature. Upon cooling below 23.6°C it undergoes a transition from the liquid crystalline phase to the solid rippled phase, characterized by periodic corrugations of the bilayer. — NCATS

Clinical trial activity

0 trials · 0 clinical orgs · 0 marketing orgs

Phase 1

Phase 2

Phase 3

Phase 4

Indications

Approved for

Chemistry & pharmacology

Loading structure…

SMILES

CCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCC

Mol. weight: 677.9325 g/mol
Lipinski Ro5: 2 violation(s)
Rule of 3: No
Chirality: Single Stereoisomer
Inorganic: No
Polymer: No
Delivery: Parenteral
Availability: Discontinued

Oral

Parenteral

Yes

Topical

Sources

Also known as

dimyristoyl glycerophosphocholine
dimyristoyllecithin
dimyristoyl lecithin
dimyristoyl lecithin
dimyristoyl lecithin
dimyristoylphosphatidylcholine
dimyristoylphosphatidylcholine
dimyristoylphosphatidylcholine
dimyristoylphosphatidylcholine
dimyristoylphosphatidylcholine
dimyristoylphosphatidylcholine, dl-
ditetradecanoylglycerophosphorylcholine
ditetradecanoylphosphatidylcholine