diamthazole
Small moleculeexperimental
Diamthazole is an antifungal drug that was used for the treatment of tinea pedis. The drug was withdrawn from the market, because it was associated with neuropsychiatric adverse reactions. — NCATS
Clinical trial activity
0 trials · 0 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Mechanism of action
- Unspecified targetOTHER
Unknown
It is not fungistatic for such organisms as Penicillium or Aspergillus but is highly effective against the pathogenic species of importance in Dermatology. Its antibacterial action was found to be negligible.
Chemistry & pharmacology
Loading structure…
SMILES
CCN(CC)CCOc1ccc2nc(N(C)C)sc2c1- Mol. weight
- 293.44 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL1184360 ↗
- NCATS3LF09TBB5W ↗
- ChEMBLCHEMBL346235 ↗
Also known as
- 6-(2-diethylaminoethylaminoethoxy)-2- dimethylaminobenzothiazole
- amikazol
- diamethazole
- diamthazole
- diamthazole
- diamthazole
- diamthazole
- diamthazole
- diamthazole dichloride
- diamthazole dihydrochloride
- diamthazole dihydrochloride
- diamthazole dihydrochloride
- diamthazole dihydrochloride
- dimazole
- dimazole
- dimazole
- dimazole
- dimazole
- dimazole dihydrochloride
- dimazole dihydrochloride
- dimazole dihydrochloride
- dimazole dihydrochloride