cr-3465
Small moleculeexperimental
Clinical trial activity
0 trials · 0 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Mechanism of action
- Cysteinyl leukotriene receptor 1ANTAGONIST
CYSLTR1 antagonist
Inhibits PDE3 and PDE4 IC50 2.01uM and 4.7uM respectively (PMID:15541426)
Chemistry & pharmacology
Loading structure…
SMILES
O=C(N[C@@H](Cc1ccc(OCc2ccc3ccc(F)cc3n2)cc1)C(=O)[O-])c1ccc2ccccc2n1.[Na+]- Mol. weight
- 517.49 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL5314389 ↗
- ChEMBLCHEMBL3545273 ↗
Also known as
- cr-3465