evans blue
Trade name: evans blue
Small moleculeapproved
Approved
Aug 6, 1971
T-1824 or Evans blue, often incorrectly rendered as Evan's blue, is an azo dye that has a very high affinity for serum albumin. Because of this, it can be useful in physiology in estimating the proportion of body water contained in blood plasma. It fluoresces with excitation peaks at 470 and 540 nm and an emission peak at 680 nm. — Wikipedia
Clinical trial activity
0 trials · 0 clinical orgs · 1 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
0
Timeline
1910s
- Jun 1, 1914
Evidence of US Marketing
1950s
- Jun 1, 1951
Parke-Davis — First NDA Organization
- Jun 1, 1951
Parke-Davis — NDA Organization
1970s
- Aug 6, 1971
Earliest FDA Approval
Indications
Approved for
Mechanism of action
- UnclearUnclear
Unclear unclear
Approval history
- approvedAug 6, 1971
- approvedJun 1, 1914
Chemistry & pharmacology
Loading structure…
SMILES
Cc1cc(-c2ccc(/N=N/c3ccc4c(S(=O)(=O)O)cc(S(=O)(=O)O)c(N)c4c3O)c(C)c2)ccc1/N=N/c1ccc2c(S(=O)(=O)O)cc(S(=O)(=O)O)c(N)c2c1O- Mol. weight
- 872.89 g/mol
- Lipinski Ro5
- 4 violation(s)
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
- Delivery
- Parenteral
- Availability
- Discontinued
Oral
No
Parenteral
Yes
Topical
No
Sources
- ChEMBLCHEMBL1015 ↗
- WikipediaEvans blue (dye) ↗
- NCATS5C44C6888V ↗
- ChEMBLCHEMBL1200712 ↗
- WikipediaEvans Blue (dye) ↗
- NCATSD56DN867MV ↗
Also known as
- azovan blue
- azovan blue
- azovan blue
- azovan sodium
- azovan sodium
- diazol pure blue bf
- direct blue 53
- evan's blue
- evan's blue
- evan's blue
- evan's blue
- evans blue
- evans blue
- evans blue
- evans blue
- evans blue
Organizations
Marketing (1)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| Parke-Davis | For profit | NDA | Jun 1, 1951 |