antazoline phosphate
Trade name: Vasocon A
Approved
Apr 30, 1990
Antazoline is a 1st generation antihistamine with anticholinergic properties used to relieve nasal congestion and in eye drops, usually in combination with naphazoline, to relieve the symptoms of allergic conjunctivitis. To treat allergic conjunctivitis, antazoline can be combined in a solution with tetryzoline. The drug is a Histamine H1 receptor antagonist: selectively binding to but not activating the receptor, thereby blocking the actions of endogenous histamine and subsequently leading to the temporary relief of the negative symptoms brought on by histamine. — Wikipedia
Clinical trial activity
0 trials · 0 clinical orgs · 1 marketing orgs
Timeline
Indications
Approved for
Mechanism of action
- Histamine H1 receptorANTAGONIST
HRH1 antagonist
Combination products
vasocon-a
with naphazoline
Approval history
- approvedApr 30, 1990
Chemistry & pharmacology
SMILES
O=P(O)(O)O.c1ccc(CN(CC2=NCCN2)c2ccccc2)cc1- Mol. weight
- 363.35 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
- Delivery
- Topical
- Availability
- Discontinued
Oral
No
Parenteral
No
Topical
Yes
Sources
- WikipediaAntazoline ↗
- ChEMBLCHEMBL1200550 ↗
Also known as
- antazoline phosphate
- antazoline phosphate
- antazoline phosphate